A reference library, published by a surgeon

We grade the evidence on facial rejuvenation. Here is what actually works.

20 treatments, each with a plain-language verdict, a grade for the quality of the human evidence, its citations, and the date I last read the literature on it.

Open the index
Fractional CO2 ResurfacingWorksEvidence grade BThe most reliably effective resurfacing tool available, with a recovery that matches the size of the effect.
Red Light TherapyModestEvidence grade BReal but small, and only with consistent use at an adequate dose.
PDO Thread LiftsThin evidenceEvidence grade CA small, short-lived repositioning effect that is consistently oversold as an alternative to surgery.
Daily SunscreenWorksEvidence grade ARandomized evidence that daily use measurably slows visible aging over years.
At-Home HIFU DevicesDoesn'tEvidence grade DEither the energy is too low to do what is claimed, or it is high enough to be a burn risk without imaging.

See all 20 treatments and their grades →

Trending

All news

Our words, the publisher's link, and the guide each one belongs to.

Start here

All guides

The guides that answer most of what people arrive wanting to know. Each one is dated, and each one gets reviewed on a schedule.

SMASDeep planeTWO LAYERS, TWO OPERATIONS
GuideFacelift & Neck

Deep Plane or SMAS: What Actually Differs, and Who Each One Suits

Both operations are called facelifts and both are done by good surgeons. The difference is which anatomical layer carries the lift, and that one decision changes the look, the durability, the scar and the risk profile.

Last reviewed 15 September 2026

CheekLipsJawWHERE IT GOES
GuideInjectables

Which Filler Goes Where — and Why the Brand Matters Less Than the Plane

The brand on the syringe is the least useful thing about a filler treatment. What decides how it looks, how long it lasts and whether it can be undone is which region it went into and which layer it was placed in. Here is the map.

Last reviewed 15 September 2026

FAT COMPARTMENTS
GuideVolume & Fat Transfer

GLP-1 Weight Loss and the Face: What Empties, and What Puts It Back

The medication is not damaging your face. Fast weight loss is, and it does it through discrete fat compartments that empty at different rates. That mechanism decides which treatments can realistically restore it.

Last reviewed 15 September 2026

EpidermisDermisFatSMASHOW DEEP EACH REACHES
GuideEnergy & Resurfacing

Fractional CO2 Recovery, Day by Day: What the Two Weeks Actually Look Like

The most powerful resurfacing tool we have, and the one most often used on the wrong patient. Here is what the treatment does to skin, who it suits, and an honest day-by-day account of the recovery nobody describes in advance.

Last reviewed 15 September 2026

The things a paragraph cannot do. Click around them.

CLICK A REGIONPlane, longevity, reversibility
ToolInjectables

Where Filler Actually Goes

Click a region of the face to see which product classes belong there, how long they last, whether they can be reversed, and what overfilling that region looks like.

DOWNTIME vs RESULT14 days10
ToolEnergy & Resurfacing

What Can You Do With One Week Off?

Every modality plotted against real downtime and the size of the change it makes. Filter by what you are actually trying to fix.

40s50s60sWORTH ITUSUALLY NOTWhat to stop paying for
ToolLongevity & Facial Aging

What Is Worth Doing in Your 40s, 50s and 60s

What tends to be worth the money at each stage — and what people keep paying for after it has stopped doing anything.

Newsletter

The one email a week that isn't selling you something.

What changed in facial rejuvenation this week, one guide we updated, and why it matters. Written by Jay Keni, MD.

A weekly email, once we launch it. We don’t sell or share addresses, and we never add patients from practice records — privacy.